看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯,血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。
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Currently available feasibility data for possible combination strategies.
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Combination Feasibility according to preliminary data : X) q2 N( ^; W4 K0 C5 m/ i# E
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Bevacizumab + sorafenib Yes, reduced dose y6 X, Z$ t# G
Bevacizumab + sunitinib† No 5 M$ L3 Q* ~9 n+ r7 Y Z
Bevacizumab + temsirolimus Yes {9 D+ w- X3 {$ L1 |# X' } Y4 o* o5 Z
Bevacizumab + everolimus Yes
6 m- @. b' n) H1 fSorafenib + sunitinib ?
- T; a2 a9 I' N; b' B5 A5 {% Z4 |Sorafenib + temsirolimus Yes, reduced dose & ]) m8 l/ }& q; `
Sorafenib + everolimus Yes, reduced dose
8 Y7 Q' M, |1 oSunitinib + temsirolimus† No
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Temsirolimus + everolimus ? ' H" a; [- G7 j* k* n* J; Y* A
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†Led to US FDA warning.
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